NON-ISOPRENOID CONSTITUENTS
(Poly) phenolics
Flavonoids: The neem leaves were reported to contain two flavonoids, quercetin20 and
Isorhamnetin131. The flowers were reported to contain kaempferol, myricetin an
quercetin62,153 The occurrence of a new isoprenylated flavanone, nimbaflavone (128,
8,3'-di-isoprenyl -5,7-dihydroxy-4'-methoxyflavanone) in leaves is reported and this is
the first report of an isoprenyl
Flavanone from Meliaceae an~ strengthens its taxonomic proximity with Rutacete50.
Flavonolglycosides: The occurrence of glycosides of kaempferol and quercetin in
flowers and leaves and that of myricetin in leaves and pure neem oil is reported. They
are quercetin-3-galactoside, kaempferol-3-glucoside and myricetin 3' -L-arabinoside
149.
Dihydrochalcone: From the aqueous fraction of the fruits, nimbochalcin (129), a dihydro
chalcone derivative was isolated 131.
Tannins: Condensed tannins to the extent of 15% were reported to occur in bark62.
Aqueous extract of bark contained gallic, acid, (+) gallocatechin, (-) epicatechin, (+)
catechin and epigallocatechin. Gallic ~cid, (-) epicatechin and (+) .catechin were
shown to inhibit the generation of chemiluminescence by activated. human
polymorphonuclear leukocytes .158
Coumarin: There is only one report on the occurrence of a coumarin, scopoletin
(7-hydroxy-6-methoxy coumarin) in leaves139