Neem oil is obtained by pressing fruits or seed on Neem Tree (Azadirchta Indica).
Pure neem oil is brownish in color and have pungent smell and bitter in taste.
Neem elaborates a vast array of biologically active compounds which are chemically diverse
and structurally complex. Many reviews have appeared from time to time on its constituents
in general and meliacins in particular.
Neem chemistry dates back to 1880-90 when influenced by its folklore medicinal values, the
chemists took up the isolation of active principles from its seed and other parts. Siddiqui
was the first to report the isolation of three products namely nimbin, nimbidin and nimbinin
from Neem Oil.
Developments since 1960 have been breath taking essentially because of the induction of
modern methods of separation and structure elucidation, as has been the case with natural
products chemistry in general. Nuclear magnetic resonance, especially its later
two-dimensional versions, has played the most outstanding role.
The neem constituents belonging to chemically diverse classes have been divided into two
major sections viz. isoprenoids, and others. The latter category comprises glycerides,
polysaccharides, sulphurous compounds, flavonoids and their glycosides, amino acids,
aliphatic compounds etc.
Over 125 such chemical constituents have been reported so far from Neem. Neem is
perhaps the only plant in the whole plant kingdom that possesses such diverse biodynamic
compounds having diseases preventive, health promotive and curative properties.